Title: Carbetapentane
CAS Registry Number: 77-23-6
CAS Name: 1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester
Additional Names: 2-(diethylaminoethoxy)ethyl 1-phenyl-1-cyclopentanecarboxylate; 2-(diethylaminoethoxy)ethyl 1-phenylcyclopentyl-1-carboxylate; 1-phenylcyclopentane-1-carboxylic acid diethylaminoethoxyethyl ester; pentoxyverine; pentoxiverin
Molecular Formula: C20H31NO3
Molecular Weight: 333.47
Percent Composition: C 72.03%, H 9.37%, N 4.20%, O 14.39%
Literature References: Prepn: H. G. Morren, GB 753779; idem, US 2842585 (1956, 1958 both to Union Chimique Belge). Antispasmodic activity: D. Wellens, Arzneim.-Forsch. 17, 495 (1967). Clinical effect on lung function: E. Krieger, ibid. 22, 389 (1972).
Properties: bp0.01 165-170°.
Boiling point: bp0.01 165-170°
Derivative Type: Citrate
CAS Registry Number: 23142-01-0
Manufacturers' Codes: UCB-2543
Trademarks: Antees (Oriental); Calnathal; Carbetane (Toyo Jozo); Cossym (Egnaro); Fustpentane; Germapect (Thiemann); Pencal (Tatsumi); Sedotussin (UCB); Toclase (Pfizer); Tosnone (Nippon Shoji); Tuclase (Pfizer)
Molecular Formula: C20H31NO3.C6H8O7
Molecular Weight: 525.59
Percent Composition: C 59.41%, H 7.48%, N 2.66%, O 30.44%
Properties: Crystals, mp 93°. Freely sol in water, chloroform; sol in alcohol, acetone, ethyl acetate. Practically insol in ether, petr ether, benzene.
Melting point: mp 93°
Therap-Cat: Antitussive.
Keywords: Antitussive. |