Title: b-Benzalbutyramide
CAS Registry Number: 7236-47-7
CAS Name: 3-Methyl-4-phenyl-3-butenamide
Additional Names: 3-methyl-4-phenyl-3-butenoic acid amide; b-benzylidenebutyramide
Trademarks: Kata-Lipid (IBI)
Molecular Formula: C11H13NO
Molecular Weight: 175.23
Percent Composition: C 75.40%, H 7.48%, N 7.99%, O 9.13%
Literature References: Prepn of the acid: Canonica et al., Farmaco Ed. Sci. 14, 112 (1959); Datta, Bagchi, J. Org. Chem. 25, 932 (1960). Clinical studies in atherosclerotic patients: F. Del Regno, G. Capobianco, Minerva Med. 54, 2917 (1963); A. Iacobelli et al., G. Arterioscler. 4, 277 (1966); M. G. Piccardo et al., ibid. 294. Metabolism: L. Canonica et al., J. Biol. Chem. 243, 1645 (1968). Inhibition of cholesterol biosynthesis: D. Giorgini, G. Porcellati, Farmaco Ed. Sci. 24, 392 (1969). Clinical evaluation in hyperlipidemia: U. Marini et al., Farmaco Ed. Prat. 36, 532 (1981).
Properties: Crystals, mp 132-134°. uv max: 249 nm (log e 4.1).
Melting point: mp 132-134°
Absorption maximum: uv max: 249 nm (log e 4.1)
Therap-Cat: Antilipemic.
Keywords: Antilipemic.
Status: This monograph has been retired and is no longer subject to revision or update. |