Title: a-Bromobutyric Acid
CAS Registry Number: 80-58-0
CAS Name: 2-Bromobutanoic acid
Additional Names: dl-2-bromobutyric acid
Molecular Formula: C4H7BrO2
Molecular Weight: 167.00
Percent Composition: C 28.77%, H 4.22%, Br 47.85%, O 19.16%
Line Formula: CH3CH2CHBrCOOH
Literature References: Prepd by bromination of butyric acid: Naumann, Ann. 119, 115 (1861); Stevens, Holland, J. Org. Chem. 18, 1112 (1953); Smissman, J. Am. Chem. Soc. 76, 5805 (1954). Toxicity study: J. L. Morrison, J. Pharmacol. Exp. Ther. 86, 336 (1946).
Properties: Oily liquid, mp -4°. bp250 181-182°, bp25 127-128°. d44 1.5855, d1515 1.5735, d2020 1.5669, d2525 1.5620: Perkin, J. Chem. Soc. 65, 402 (1894). Boils with decompn at ordinary pressure. Sol in 15 parts water; sol in alcohol, ether. Corrosive! LD50 orally in mice: 310 mg/kg (Morrison).
Melting point: mp -4°
Boiling point: bp250 181-182°; bp25 127-128°
Density: d44 1.5855; d1515 1.5735; d2020 1.5669; d2525 1.5620
Toxicity data: LD50 orally in mice: 310 mg/kg (Morrison)
Derivative Type: Ethyl ester
Additional Names: Ethyl a-bromobutyrate
Molecular Formula: C6H11BrO2
Molecular Weight: 195.05
Percent Composition: C 36.95%, H 5.68%, Br 40.97%, O 16.41%
Properties: Liquid, bp 177-178° with slight dec. d2020 1.329. Insol in water. Misc with alc, ether. Protect from light. Lacrimator!
Boiling point: bp 177-178° with slight dec
Density: d2020 1.329
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