Title: Alloxantin
CAS Registry Number: 76-24-4
CAS Name: 5,5¢-Dihydroxy-[5,5¢-bipyrimidine]-2,2¢,4,4¢,6,6¢(1H,1¢H,3H,3¢H,5H,5¢H)-hexone
Additional Names: 5,5¢-dihydroxy-5,5¢-bibarbituric acid; uroxin
Molecular Formula: C8H6N4O8
Molecular Weight: 286.16
Percent Composition: C 33.58%, H 2.11%, N 19.58%, O 44.73%
Literature References: Prepd from uric acid: Nightingale, Org. Synth. coll. vol. III, 42 (1955); from alloxan monohydrate: Tipson, ibid. coll. vol. IV, 25 (1963). Structure: Singh, Acta Crystallogr. 19, 767 (1965).
Derivative Type: Dihydrate
Properties: Cryst powder. On exposure to air becomes red. Becomes yellow at 225°; dec at 253-255°. Sparingly sol in cold water, alcohol or ether. Its aq soln is acid; reduces Ag salts and gives a blue ppt with Ba(OH)2 soln. Keep tightly closed. Emits toxic fumes upon decompn.
CAUTION: Ingestion causes disturbed carbohydrate metabolism leading to diabetes, cf. Dangerous Properties of Industrial Materials, N. I. Sax, Ed. (Van Nostrand Reinhold, New York, 4th ed., 1975) p 366. |