Title: Acediasulfone
CAS Registry Number: 80-03-5
CAS Name: N-[4-[(4-Aminophenyl)sulfonyl]phenyl]glycine
Additional Names: N-p-sulfanilylphenylglycine; p-amino-p¢-(carboxymethylamino)diphenyl sulfone; 4-carboxymethylamino-4¢-aminodiphenylsulfone; diaminodiphenylsulfone-N-acetic acid
Molecular Formula: C14H14N2O4S
Molecular Weight: 306.34
Percent Composition: C 54.89%, H 4.61%, N 9.14%, O 20.89%, S 10.47%
Literature References: Prepn: Jackson, J. Am. Chem. Soc. 70, 680 (1948); CH 254803 and CH 278482 (1949, 1952, to Cilag Ltd.); Rawlins, US 2589211 (1952 to Parke, Davis).
Properties: Crystals, mp 194°. Sol in methanol, dil sodium hydroxide, acetone.
Melting point: mp 194°
Derivative Type: Sodium salt
CAS Registry Number: 127-60-6
Trademarks: Sulfon-Cilag
Molecular Formula: C14H13N2NaO4S
Molecular Weight: 328.32
Percent Composition: C 51.22%, H 3.99%, N 8.53%, Na 7.00%, O 19.49%, S 9.77%
Derivative Type: Morpholine salt
Trademarks: Bentrofene (Cilag-Chemie)
Molecular Formula: C18H23N3O5S
Molecular Weight: 393.46
Percent Composition: C 54.95%, H 5.89%, N 10.68%, O 20.33%, S 8.15%
Literature References: Prepn: Martin, Habicht, US 2751382 (1956 to Cilag Ltd.).
Properties: Glittering crystals, mp 133-135° (dec).
Melting point: mp 133-135° (dec)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Sulfones. |