Zinc Sulfate
Title: Zinc Sulfate
CAS Registry Number: 7733-02-0
Additional Names: White vitriol; zinc vitriol
Molecular Formula: O4SZn
Molecular Weight: 161.47
Percent Composition: O 39.63%, S 19.86%, Zn 40.51%
Line Formula: ZnSO4
Literature References: Prepn and physical properties: Gmelins, Zink (8th ed.) 32, 936-960 (1956). Effects of oral zinc sulfate in acne treatment: G. Michaelsson et al., Arch. Dermatol. 113, 31 (1977). Clinical evaluations in Wilson's Disease: T. U. Hoogenraad, C. J. A. Van den Hamer, Acta Neurol. Scand. 67, 356 (1983); T. U. Hoogenraad et al., J. Neurol. Sci. 77, 137 (1987).
 
Derivative Type: Monohydrate
CAS Registry Number: 7446-19-7
Additional Names: Dried zinc sulfate
Trademarks: Zincaps (RPR); Z Span (Goldshield)
Properties: Powder or granules. Loses H2O above 238°. Sol in water. Practically insol in alcohol.
 
Derivative Type: Heptahydrate
CAS Registry Number: 7446-20-0
Trademarks: Collazin (Vitaplex); Keratol (Streuli); Op-Thal-Zin (Alcon); Redeema (Merz); Solvazinc (Thames); Solvezink (Tika); Virudermin (Robugen); Zincate (Paddock); Zincomed (Schwarz)
Properties: Odorless crystals or granules or powder; astringent taste. Efflorescent in dry air. d 1.97. mp 100°. At 280° loses all H2O; dec above 500°. One gram dissolves in 0.6 ml water, 2.5 ml glycerol. Insol in alcohol. The aq soln is acid to litmus; pH about 4.5. Keep well closed.
Melting point: mp 100°
Density: d 1.97
 
NOTE: The monohydrate does not cake as the heptahydrate does, and hence is more convenient for use during the warm season and in warm climates.
CAUTION: Irritating to skin, mucous membranes: H. E. Stokinger, Patty's Industrial Hygiene and Toxicology 2A, G. D. Clayton, F. E. Clayton, Eds. (John Wiley & Sons, New York, 1981) pp 2033-2049.
Use: As mordant in calico-printing; preserving wood and skins; with hypochlorite for bleaching paper; manuf lithopone and other zinc salts; clarifying glue; electrodepositing Zn; also as reagent in analytical chemistry.
Therap-Cat: Ophthalmic astringent. Zinc supplement.
Therap-Cat-Vet: Astringent. Has been used as an emetic.
Keywords: Astringent; Replenishers/Supplements; Zinc.

Others monographs:
LanatosidesSaunders, Red2,3-Diaminopropionic AcidNifurfoline
IsaxoninePotassium Tungstate(VI)Ethyl SalicylateRubidium Iodide
Sulfarside1,2,4-BenzenetriolClofibrateDomesticine
Malonic Acidn-HexanePropiolic AcidAcrylamide
©2016 DrugLead US FDA&EMEA