Title: Triparanol
CAS Registry Number: 78-41-1
CAS Name: 4-Chloro-a-[4-[2-(diethylamino)ethoxy]phenyl]-a-(4-methylphenyl)benzeneethanol
Additional Names: 1-[p-(2-diethylaminoethoxy)phenyl]-1-(p-tolyl)-2-(p-chlorophenyl)ethanol; 2-(p-chlorophenyl)-1-[p-(2-diethylaminoethoxy)phenyl]-1-(p-tolyl)ethanol
Manufacturers' Codes: MER-29
Trademarks: Trianel; Hipocolestina; Triparin; Acosterina; Metasclene; Diticyl; Drenaren; Clotrox; Tropalin; Trikosterol; Valip; Verdiana; Metasqualene; Sclane
Molecular Formula: C27H32ClNO2
Molecular Weight: 438.00
Percent Composition: C 74.04%, H 7.36%, Cl 8.09%, N 3.20%, O 7.31%
Literature References: Prepn: Allen, Palopoli et al., US 2914562 (1959 to Wm. S. Merrell).
Properties: Crystals, mp 102-104°. Sol in alcohol; slightly sol in olive oil; practically insol in water.
Melting point: mp 102-104°
CAUTION: Withdrawn from market because of association with formation of irreversible cataracts; see Laughlin, Carey, J. Am. Med. Assoc. 181, 339 (1962).
Therap-Cat: Antilipemic.
Keywords: Antilipemic.
Status: This monograph has been retired and is no longer subject to revision or update. |