Title: Trimipramine
CAS Registry Number: 739-71-9
CAS Name: 10,11-Dihydro-N,N,b-trimethyl-5H-dibenz[b,f]azepine-5-propanamine
Additional Names: 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine; 5-(3-dimethylamino-2-methylpropyl)iminodibenzyl; trimeprimine; trimeproprimine
Manufacturers' Codes: RP-7162
Trademarks: Sapilent (EGYT)
Molecular Formula: C20H26N2
Molecular Weight: 294.43
Percent Composition: C 81.59%, H 8.90%, N 9.51%
Literature References: Prepn: Jacob, Messer, Compt. Rend. 252, 2117 (1961). Toxicity studies: Okamoto, C.A. 72, 77299y (1970). Chemistry: Bever, Bredenstein, Dtsch. Apoth. Ztg. 113, 1562 (1973). Comprehensive description of the maleate: A. A. Al-Badr, Anal. Profiles Drug Subs. 12, 683-712 (1983).
Properties: Crystals, mp 45°.
Melting point: mp 45°
Derivative Type: Maleate
CAS Registry Number: 521-78-8
Trademarks: Stangyl (tabl) (Rhone-Poulenc); Surmontil (tabl) (Rhone-Poulenc)
Molecular Formula: C20H26N2.C4H4O4
Molecular Weight: 410.51
Percent Composition: C 70.22%, H 7.37%, N 6.82%, O 15.59%
Properties: Crystals, mp 142°. Sol in chloroform; slightly sol in water, ethanol. Practically insol in ether.
Melting point: mp 142°
Derivative Type: Methanesulfonate
Trademarks: Stangyl (amp) (Rhone-Poulenc); Surmontil (amp) (Rhone-Poulenc)
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics. |