Title: Triclabendazole
CAS Registry Number: 68786-66-3
CAS Name: 5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole
Manufacturers' Codes: CGA-89317
Trademarks: Fasinex (Novartis)
Molecular Formula: C14H9Cl3N2OS
Molecular Weight: 359.66
Percent Composition: C 46.75%, H 2.52%, Cl 29.57%, N 7.79%, O 4.45%, S 8.92%
Literature References: Benzimidazole derivative effective against liver fluke. Prepn: J.-J. Gallay et al., BE 865870 corresp to US 4197307 (1978, 1980 both to Ciba-Geigy). Efficacy against immature and mature Fasciola hepatica in sheep, goats: K. Wolff et al., Vet. Parasitol. 13, 145 (1983); in sheep: J. C. Boray et al., Vet. Rec. 113, 315 (1983). Effective also against F. gigantica in sheep: N. Güralp, R. Tinar, J. Helminthol. 58, 113 (1984). Brief review: J. Eckert et al., Biol. Muench. Tieraerztl. Wochenschr. 97, 349 (1984).
Properties: Crystals, mp 175-176°.
Melting point: mp 175-176°
Therap-Cat-Vet: Anthelmintic (fasciola). |