Title: Tranylcypromine
CAS Registry Number: 155-09-9
CAS Name: (1R,2S)-rel-2-Phenylcyclopropanamine
Manufacturers' Codes: SKF-385
Molecular Formula: C9H11N
Molecular Weight: 133.19
Percent Composition: C 81.16%, H 8.32%, N 10.52%
Literature References: Monoamine oxidase inhibitor. Prepn: Burger, Yost, J. Am. Chem. Soc. 70, 2198 (1948); R. E. Tedeschi, US 2997422 (1961 to SK & F).
Properties: Liquid, bp1.5-1.6 79-80°.
Boiling point: bp1.5-1.6 79-80°
Derivative Type: Hydrochloride
Molecular Formula: C9H11N.HCl
Molecular Weight: 169.65
Percent Composition: C 63.72%, H 7.13%, N 8.26%, Cl 20.90%
Properties: Crystals from ethyl acetate + ether, mp 164-166°.
Melting point: mp 164-166°
Derivative Type: Sulfate
CAS Registry Number: 13492-01-8
Trademarks: Parnate (GSK); Tylciprine (Thaplix)
Molecular Formula: (C9H11N)2.H2SO4
Molecular Weight: 364.46
Percent Composition: C 59.32%, H 6.64%, N 7.69%, S 8.80%, O 17.56%
Properties: Crystals, sol in water; very slightly sol in alcohol, ether. Practically insol in chloroform.
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Monoamine Oxidase Inhibitor. |