Title: Stryker's Reagent
CAS Registry Number: 33636-93-0
CAS Name: Octahedrohexa-m3-hydrohexakis(triphenylphosphine)hexacopper
Additional Names: hexa-m-hydrohexakis(triphenylphosphine) hexacopper; triphenylphosphine copper(I) hydride hexamer
Molecular Formula: C108H96Cu6P6
Molecular Weight: 1961.04
Percent Composition: C 66.15%, H 4.93%, Cu 19.44%, P 9.48%
Line Formula: [(C6H5)3PCuH]6
Literature References: Copper(I) hydride cluster; mild hydride donor in organic synthesis. Prepn and crystal characterization: S. A. Bezman et al., J. Am. Chem. Soc. 93, 2063 (1971); M. R. Churchill et al., Inorg. Chem. 11, 1818 (1972). Improved prepns: D. M. Brestensky et al., Tetrahedron Lett. 29, 3749 (1988); P. Chiu et al., ibid. 44, 455 (2003). Use in reduction of a,b-unsaturated carbonyl compds: W. S. Mahoney et al., J. Am. Chem. Soc. 110, 291 (1988); W. S. Mahoney, J. M. Stryker, ibid. 111, 8818 (1989); in hydrosilylation of aldehydes and ketones: B. H. Lipshutz et al., J. Organomet. Chem. 624, 367 (2001). Brief review: A. de Fátima, Synlett 2005, 1805-1806 (2005).
Properties: Isolated as H6Cu6(PPh3)6.DMF. Bright red crystals, mp 111° (dec). d 1.367. Sol in benzene; slightly sol in DMF. Insol in acetonitrile, water. Dec in alcohols, ethers, chlorinated hydrocarbons. Air sensitive in soln. Store under nitrogen.
Melting point: mp 111° (dec)
Density: d 1.367
Use: Stoichiometric reducing agent or catalyst in reduction reactions. |