Title: Savin
Literature References: Young shoots of Juniperus sabina L., Cupressaceae; used in traditional medicine as emmenogogue and antirheumatic. Habit. Europe, Northern Asia, Northern U.S. Constit. 3-5% volatile oil, tannin, savinin, podophyllotoxin. Isoln and structure of savinin: Hartwell et al., J. Am. Chem. Soc. 75, 235 (1953); Schrecker, Hartwell, ibid. 76, 4896 (1954). Review: J. Gruenwald et al., PDR for Herbal Medicines (Medical Economics, Montvale, 3rd Ed., 2004) pp 706-707.
Derivative Type: Volatile oil
CAS Registry Number: 8024-00-8
Additional Names: Oil of savin
Literature References: Constit. Chiefly sabinyl acetate, sabinene; b-myrcene, terpin-4-ol, g-terpinene, a-pinene, limonene.
Properties: Colorless or pale yellow liquid. d1515 0.903-0.923. aD +40 to +60°. nD20 1.470-1.478. Very slightly sol in water; very sol in alcohol. Keep well closed, cool and protected from light.
Optical Rotation: aD +40 to +60°
Index of refraction: nD20 1.470-1.478
Density: d1515 0.903-0.923
CAUTION: Potential symptoms of overexposure include queasiness, spasm, hematuria, central paralysis, unconsciousness. External application may cause skin irritation, blistering, necrosis (Gruenwald).
Therap-Cat: In treatment of warts. |