Title:  Retine 
CAS Registry Number:  51848-43-2 
Literature References:  Inhibitor of malignant growth, extracted along with promine, a cancer growth-promoting and sterilizing substance, from calves' thymus:  A. Szent-Györgyi et al., Proc. Natl. Acad. Sci. USA 48, 1439 (1962).  Sterilizing action of promine caused by another substance, infertine:  A. Hegyeli et al., ibid. 49, 230 (1963).  Prepn from calves' aortas:  A. Szent-Györgyi et al., Science 140, 1391 (1963); from human urine:  A. Hegyeli et al., ibid. 142, 1571 (1963).  Identification studies:  L. G. Együd, Proc. Natl. Acad. Sci. USA 54, 200 (1965); A. Szent-Györgyi, ibid. 57, 1642 (1967).  Review of promine/retine theory:  M. P. Kalapos, Biochim. Biophys. Acta 1426, 1-16 (1999); of retine composition:  D. E. Douglas, J. Pharm. Pharmacol. 54, 1429-1431 (2002). 
  
  
Status:  This monograph has been retired and is no longer subject to revision or update.   |