Title: Phenacemide
CAS Registry Number: 63-98-9
CAS Name: N-(Aminocarbonyl)benzeneacetamide
Additional Names: (phenylacetyl)urea; phenacetylurea
Trademarks: Epiclase (Bellon); Phacetur; Phenurone (Abbott); Phetylureum (Katwijk)
Molecular Formula: C9H10N2O2
Molecular Weight: 178.19
Percent Composition: C 60.66%, H 5.66%, N 15.72%, O 17.96%
Line Formula: C6H5CH2CONHCONH2
Literature References: Prepd by the action of aq NH3 on phenacetylurethan: Basterfield, Greig, Can. J. Res. 8, 454 (1933); of phenacetyl chloride on urea: Spielman et al., J. Am. Chem. Soc. 70, 4189 (1948). Toxicity study: K. Nakamura et al., Arzneim.-Forsch. 18, 524 (1968).
Properties: Crystals from alcohol, mp 212-216°. Very slightly sol in water; slightly sol in alcohol, benzene, chloroform, ether. LD50 in mice, rats (mmol/kg): 5.54, >10 orally (Nakamura).
Melting point: mp 212-216°
Toxicity data: LD50 in mice, rats (mmol/kg): 5.54, >10 orally (Nakamura)
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant. |