Title: Nylidrin
CAS Registry Number: 447-41-6
CAS Name: 4-Hydroxy-a-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenemethanol
Additional Names: p-hydroxy-a-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]benzyl alcohol; p-hydroxy-N-(1-methyl-3-phenylpropyl)norephedrine; buphenine; 1-(p-hydroxyphenyl)-2-(1¢-methyl-3¢-phenylpropylamino)-1-propanol; phenyl-sec-butyl norsuprifen
Molecular Formula: C19H25NO2
Molecular Weight: 299.41
Percent Composition: C 76.22%, H 8.42%, N 4.68%, O 10.69%
Literature References: Prepn: FR 968273 (1950 to Troponwerke Dinklage); GB 669574; GB 669575 (1952); Chem. Eng. News 33, 2896 (1955); Külz, Schöpf, US 2661372; US 2661373 (1953). Pharmacology: T. T. Yen, D. V. Pearson, Res. Commun. Chem. Pathol. Pharmacol. 23, 11 (1979); B. Fichtl, W. Felix, Eur. J. Pharmacol. 65, 333 (1980).
Properties: Crystals from methanol, mp 111-112°.
Melting point: mp 111-112°
Derivative Type: Hydrochloride
CAS Registry Number: 849-55-8
Manufacturers' Codes: SKF-1700-A
Trademarks: Arlidin (USV); Bufedon (Cosmopharma); Buphedrin (Tatsumi); Dilatal; Dilatol (Troponwerke); Dilatropon (Draco); Dilydrin (Medichemie); Opino (Bayropharma); Penitardon (Woelm); Perdilatal (Smith & Nephew); Rudilin (Darby); Rydrin (Kodama); Tocodilydrin (Swiss Pharma); Tocodrin (Medichemie)
Molecular Formula: C19H25NO2.HCl
Molecular Weight: 335.87
Percent Composition: C 67.94%, H 7.80%, N 4.17%, O 9.53%, Cl 10.56%
Properties: Crystals. Sparingly sol in water; slightly sol in alcohol. Practically insol in ether, chloroform, benzene.
Therap-Cat: Vasodilator (peripheral).
Keywords: Vasodilator (Peripheral). |