Title: N4-Sulfanilylsulfanilamide
CAS Registry Number: 547-52-4
CAS Name: 4¢-Sulfamoylsulfanilanilide
Additional Names: 4-aminobenzenesulfono-p-sulfamoylanilide; 4-(4¢-aminobenzenesulfonamido)benzenesulfonamide
Manufacturers' Codes: DB-32
Trademarks: Diseptal C; Uliron C; Disulon (Specia); Neosanamid II; Albasil C; Disulfan
Molecular Formula: C12H13N3O4S2
Molecular Weight: 327.38
Percent Composition: C 44.02%, H 4.00%, N 12.84%, O 19.55%, S 19.59%
Literature References: Prepn: FR 817034 (to I. G. Farben.), C.A. 32, 1714i (1938); Sakai, Yamamoto, J. Pharm. Soc. Jpn. 58, 683 (1938); Golovchinskaya, J. Appl. Chem. USSR 18, 647 (1945); Sasa, J. Soc. Org. Syn. Chem. Jpn. 12, 211 (1954), C.A. 51, 2780h (1957); Grigorovskii, Dykhanov, J. Appl. Chem. USSR 30, 1284 (1957).
Properties: Needles from water, mp 133-134°. Absorption max: Maschka et al., Monatsh. Chem. 84, 1071 (1953). Slightly sol in cold water; considerably more sol in hot water. Sol in methanol, ethanol, ether, dil NH3, dil HCl; practically insol in petr ether, chloroform.
Melting point: mp 133-134°
NOTE: The name Disulon is also used for disulfanilamide, H2NC6H4SO2NHSO2C6H4NH2, esp. in the French literature.
Therap-Cat: Antibacterial (topical).
Keywords: Antibacterial (Synthetic); Sulfonamides. |