Title: Methyl N-Methylnipecotate
CAS Registry Number: 1690-72-8
CAS Name: 1-Methyl-3-piperidinecarboxylic acid methyl ester
Additional Names: N-methylnipecotic acid methyl ester; dihydroarecoline
Molecular Formula: C8H15NO2
Molecular Weight: 157.21
Percent Composition: C 61.12%, H 9.62%, N 8.91%, O 20.35%
Literature References: Prepn: Stoll et al., Helv. Chim. Acta 33, 375 (1950); Sperber et al., J. Am. Chem. Soc. 81, 704 (1959). Electron distribution and dissociation constants: E. Mutschler et al., Arzneim.-Forsch. 17, 833 (1967). Pharmacologic studies: O. Nieschulz, ibid. 22, 804 (1972). Structure-conformation activity study: G. Lambrecht, E. Mutschler, ibid. 24, 1725 (1974).
Properties: Oil, bp12 83-84°. nD25 1.4520. pKa (20°): 8.66.
Boiling point: bp12 83-84°
pKa: pKa (20°): 8.66
Index of refraction: nD25 1.4520
Derivative Type: Methobromide
CAS Registry Number: 60296-01-7
Trademarks: Adipsin (Heilmittelwerke)
Molecular Formula: C9H18BrNO2
Molecular Weight: 252.15
Percent Composition: C 42.87%, H 7.20%, Br 31.69%, N 5.55%, O 12.69%
Therap-Cat: Sialagogue.
Status: This monograph has been retired and is no longer subject to revision or update. |