Title: Mecloralurea
CAS Registry Number: 1954-79-6
CAS Name: N-Methyl-N¢-(2,2,2-trichloro-1-hydroxyethyl)urea
Additional Names: trichloroethylolmethylurea
Trademarks: Heraldium (Sanofi)
Molecular Formula: C4H7Cl3N2O2
Molecular Weight: 221.47
Percent Composition: C 21.69%, H 3.19%, Cl 48.02%, N 12.65%, O 14.45%
Literature References: Prepn from chloral hydrate and N-methylurea: Chattaway, James, J. Chem. Soc. 1934, 109; FR M5341; GB 1129437 corresp to Castaigne, US 3510557 (1967, 1968 and 1970 to Centre d'Etudes l'Ind. Pharm.).
Properties: White crystalline powder from boiling water, mp 135-140°. Partly sol in water, acetic acid, ether; sol in alcohol, pyridine. Practically insol in hydrocarbons and chloroform.
Melting point: mp 135-140°
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic.
Status: This monograph has been retired and is no longer subject to revision or update. |