Title: Idrocilamide
CAS Registry Number: 6961-46-2
CAS Name: N-(2-Hydroxyethyl)-3-phenyl-2-propenamide
Additional Names: N-(2-hydroxyethyl)cinnamamide
Manufacturers' Codes: LCB-29
Trademarks: Brolitène (Lab. Medicia); Srilane (Medicia)
Molecular Formula: C11H13NO2
Molecular Weight: 191.23
Percent Composition: C 69.09%, H 6.85%, N 7.32%, O 16.73%
Literature References: Prepn: M. Bayssat et al., DE 2015447; eidem, US 3659014 (1970, 1972 to LIPHA); Chim. Ther. 8, 202 (1973). Pharmacology: Grand et al., Eur. J. Med. Chem. 9, 205 (1974). Metabolism: Belleville et al., Therapie 29, 829 (1974).
Properties: White crystals from ethyl acetate or acetone, mp 100-102°. Soluble in alcohol; slightly sol in water. LD50 orally in mice, rats: >2950, >3000 mg/kg (Grand).
Melting point: mp 100-102°
Toxicity data: LD50 orally in mice, rats: >2950, >3000 mg/kg (Grand)
Therap-Cat: Muscle relaxant (skeletal).
Keywords: Muscle Relaxant (Skeletal). |