Title: Glybuthiazol(e)
CAS Registry Number: 535-65-9
CAS Name: 4-Amino-N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
Additional Names: N1-(5-tert-butyl-1,3,4-thiadiazol-2-yl)sulfanilamide; sulfatertiobutylthiadiazole; 2-(p-aminobenzenesulfamido)-5-tertiobutyl-1,3,4-thiadiazole; glybuthizol
Manufacturers' Codes: RP-2259
Trademarks: Glipasol
Molecular Formula: C12H16N4O2S2
Molecular Weight: 312.41
Percent Composition: C 46.13%, H 5.16%, N 17.93%, O 10.24%, S 20.53%
Literature References: Prepn: GB 828963 (1960 to Rhône-Poulenc).
Properties: Needles from ethanol, mp 221-223°. Sol in ethanol (1.0 g/65 ml); in acetone (1.0 g/15 ml); in DMF (1.0 g/3 ml). Insol in water, ether, benzene. Forms a water-sol Na salt.
Melting point: mp 221-223°
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Sulfonylurea Derivatives. |