Title: Dimethirimol
CAS Registry Number: 5221-53-4
CAS Name: 5-Butyl-2-(dimethylamino)-6-methyl-4(1H)-pyrimidinone
Additional Names: 5-butyl-2-(dimethylamino)-6-methyl-4-pyrimidinol; 2-dimethylamino-4-methyl-5-n-butyl-6-hydroxypyrimidine
Manufacturers' Codes: PP-675
Trademarks: Milcurb (Zeneca)
Molecular Formula: C11H19N3O
Molecular Weight: 209.29
Percent Composition: C 63.13%, H 9.15%, N 20.08%, O 7.64%
Literature References: Prepn: B. K. Snell et al., ZA 6701373; eidem, US 3980781 (1968, 1976 both to ICI). Systemic fungicidal activity: R. S. Elias, Nature 219, 1160 (1968); K. J. Bent, Ann. Appl. Biol. 66, 103 (1970). Metabolism and mode of action: A. Calderbank, Acta Phytopathol. 6, 355 (1971). Metabolism: H. Bratt et al., Food Cosmet. Toxicol. 10, 489 (1972).
Properties: Needles from ethanol, mp 102°. Vapor pressure at 30°: 1.1 ´ 10-5 mm Hg. uv max (methanol): 229, 304 nm (e 15500, 7700). Soly in (g/l) at 25°: water 1.2; acetone 45; chloroform 1200; ethanol 65; xylene 360. LD50 in female rats (mg/kg): 200-400 i.p., >4000 orally (Elias).
Melting point: mp 102°
Absorption maximum: uv max (methanol): 229, 304 nm (e 15500, 7700)
Toxicity data: LD50 in female rats (mg/kg): 200-400 i.p., >4000 orally (Elias)
Use: Fungicide. |