Title: Diginatigenin
CAS Registry Number: 559-57-9
CAS Name: (3b,5b,12b,16b)-3,12,14,16-Tetrahydroxycard-20(22)-enolide
Additional Names: 12-hydroxygitoxigenin; 16-hydroxydigoxigenin
Molecular Formula: C23H34O6
Molecular Weight: 406.51
Percent Composition: C 67.96%, H 8.43%, O 23.61%
Literature References: Aglycone of diginatin from Digitalis lanata Ehrk., Scrophulariaceae: Murphy, J. Am. Pharm. Assoc. Sci. Ed. 44, 719 (1955). Aglycone of lanatoside D: Angliker et al., Ann. 607, 131 (1957). Obtained by microbiological conversion of gitoxigenin: Tamm, Gubler, Helv. Chim. Acta 41, 1762 (1958); Okado et al., Chem. Pharm. Bull. 8, 530 (1960). Structure: Linde et al., Helv. Chim. Acta 42, 2040 (1959); Okado et al., Chem. Pharm. Bull. 8, 535 (1960).
Properties: Needles from water, mp 157°. [a]D20 +34° (methanol). Absorption max (ethanol): 318 nm (log e 4.18); (98% w/w H2SO4): 230, 310, 390, 490 nm (E1%1cm 160, 130, 210, 85).
Melting point: mp 157°
Optical Rotation: [a]D20 +34° (methanol)
Absorption maximum: Absorption max (ethanol): 318 nm (log e 4.18); (98% w/w H2SO4): 230, 310, 390, 490 nm (E1%1cm 160, 130, 210, 85) |