Title: Dichlorophen
CAS Registry Number: 97-23-4
CAS Name: 2,2¢-Methylenebis[4-chlorophenol]
Additional Names: 2,2¢-dihydroxy-5,5¢-dichlorodiphenylmethane; 5,5¢-dichloro-2,2¢-dihydroxydiphenylmethane; bis[5-chloro-2-hydroxyphenyl]methane; di[5-chloro-2-hydroxyphenyl]methane; dichlorophene
Manufacturers' Codes: G-4
Trademarks: Anthiphen; Dicestal; Didroxane; Di-phenthane-70; Parabis (Dow); Plath-Lyse (G¢rier); Preventol G-D; Wespuril (Spitzner)
Molecular Formula: C13H10Cl2O2
Molecular Weight: 269.12
Percent Composition: C 58.02%, H 3.75%, Cl 26.35%, O 11.89%
Literature References: Prepn by adding a CH2O yielding reagent, e.g. aq HCHO, to p-chlorophenol: Gump, Luthy, US 2334408 (1944 to Burton T. Bush). Acute toxicity: T. B. Gaines, R. E. Linder, Fundam. Appl. Toxicol. 7, 299 (1986).
Properties: Crystals from toluene, mp 177-178°. Practically insol in water. Sparingly sol in toluene. One gram dissolves in 1 g of 95% ethanol, in less than 1 g of ether. Also sol in methanol, isopropyl ether, petr ether. Sol (with decompn) in alkaline aq solns. LD50 in adult male, female rats (mg/kg): 1506, 1683 orally (Gaines, Linder).
Melting point: mp 177-178°
Toxicity data: LD50 in adult male, female rats (mg/kg): 1506, 1683 orally (Gaines, Linder)
Use: Agricultural fungicide; antimicrobial; germicide in soaps, shampoos, etc.
Therap-Cat: Anthelmintic (Cestodes).
Therap-Cat-Vet: Anthelmintic, antiprotozoan, fungicide.
Keywords: Anthelmintic (Cestodes). |