Title: Demanyl Phosphate
CAS Registry Number: 6909-62-2
CAS Name: Mono[2-(dimethylamino)ethyl]phosphoric acid ester
Additional Names: 2-dimethylaminoethanol dihydrogen phosphate; phosphoryldimethylaminoethanol; phosphoryldimethylcolamine; phosphoryldimethylethanolamine; P-DMEA
Trademarks: Panclar (Lematte et Boinot)
Molecular Formula: C4H12NO4P
Molecular Weight: 169.12
Percent Composition: C 28.41%, H 7.15%, N 8.28%, O 37.84%, P 18.31%
Line Formula: (CH3)2NCH2CH2OPO3H2
Literature References: Prepn: Aron-Samuel et al., FR 992802 (1951), C.A. 51, 458e (1957); Cherbuliez, Rabinowitz, Helv. Chim. Acta 41, 1168 (1958); GB 861463; US 3098072 (1961, 1963 to Ciba). The phosphate ester of a possible choline precursor. Has been isolated from a choline-requiring mutant of Neurospora crassa, strain 47904: Wolf, Nyc, J. Biol. Chem. 234, 1068 (1959). Biosynthetic studies: Ansell, Chojnacki, Nature 196, 545 (1962); eidem, Biochem. J. 98, 303 (1966).
Properties: Crystals, mp 175-176°.
Melting point: mp 175-176°
Derivative Type: Monohydrate
Properties: mp 78-81°.
Melting point: mp 78-81°
Therap-Cat: Psychotonic.
Keywords: CNS Stimulant. |