Title: Cinnamedrine
CAS Registry Number: 90-86-8
CAS Name: a-[1-[Methyl(3-phenyl-2-propenyl)amino]ethyl]benzenemethanol
Additional Names: N-cinnamylephedrine; a-[1-(N-cinnamyl-N-methylamino)ethyl]benzyl alcohol
Molecular Formula: C19H23NO
Molecular Weight: 281.39
Percent Composition: C 81.10%, H 8.24%, N 4.98%, O 5.69%
Literature References: Smooth muscle relaxant. Prepn: Stolz, Flaecher, US 1959392 (1934 to Winthrop Chem.); Welsh, Keenan, J. Am. Pharm. Assoc. Sci. Ed. 30, 123 (1941).
Derivative Type: dl-Hydrochloride
Molecular Formula: C19H23NO.HCl
Molecular Weight: 317.85
Percent Composition: C 71.80%, H 7.61%, N 4.41%, O 5.03%, Cl 11.15%
Properties: Bitter crystals from ethyl acetate + chloroform, mp 180-185° (base, mp 72-78°). Sol in about 80 parts water and 10 parts alc at 20°, more easily sol at higher temps; sol in 50 parts chloroform; sparingly sol in ether, benzene.
Melting point: mp 180-185°; (base, mp 72-78°)
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic. |