Title: Chlordan(e)
CAS Registry Number: 57-74-9
CAS Name: 1,2,4,5,6,7,8,8-Octachloro-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene
Additional Names: 1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindan; 1,2,4,5,6,7,8,8-octachloro-4,7-methane-3a,4,7,7a-tetrahydroindane; CD-68
Manufacturers' Codes: Velsicol 1068
Trademarks: Toxichlor; Niran (Tamogan); Octachlor; Ortho-Klor; Synklor; Corodane; Belt
Molecular Formula: C10H6Cl8
Molecular Weight: 409.78
Percent Composition: C 29.31%, H 1.48%, Cl 69.21%
Literature References: The commercial product is a mixture containing 60 to 75% of the pure compound and 25 to 40% of related compds. Chlorine content: 64-67%. Prepn: Hyman, GB 618432 (1949); Kleiman, US 2598561 (1952 to Velsicol). Insecticidal activity: Bussart, Schor, Soap Sanit. Chem. 24, 126 (1948). Toxicity study: R. B. Harbison, Toxicol. Appl. Pharmacol. 32, 443 (1975). Review of toxicology and human exposure: Toxicological Profile for Chlordane (PB95-100111, 1994) 262 pp.
Properties: Viscous, amber-colored liquid. Viscosity (25°): 69 P (about that of 95% glycerol). Viscosity reduced considerably by heating to 120-140°F when it may be sprayed directly. d25 1.59-1.63. nD25 1.56-1.57. Insol in water. Miscible with aliphatic and aromatic hydrocarbon solvents, including deodorized kerosene. Loses its chlorine in presence of alkaline reagents, and should not be formulated with any solvent, carrier, diluent or emulsifier, which has an alkaline reaction. LD50 i.p. in male rats: 343 mg/kg (Harbison).
Index of refraction: nD25 1.56-1.57
Density: d25 1.59-1.63
Toxicity data: LD50 i.p. in male rats: 343 mg/kg (Harbison)
CAUTION: Potential symptoms of overexposure are blurred vision; confusion; ataxia, delirium; coughing; abdominal pain, nausea, vomiting and diarrhea; irritability, tremor, convulsions; anuria. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 56. Direct contact may cause skin, eye and mucous membrane irritation. See Patty's Industrial Hygiene and Toxicology vol. 2B, G. D. Clayton, F. E. Clayton, Eds. (Wiley-Interscience, New York, 3rd ed., 1981) pp 3718-3725. See also Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section III, p 108-109.
Use: Insecticide, fumigant.
Therap-Cat-Vet: Insecticide, acaricide. |