Title: Bismuth Subsalicylate
CAS Registry Number: 14882-18-9
CAS Name: 2-Hydroxy-4H-1,3,2-benzodioxabismin-4-one
Additional Names: (2-hydroxybenzoato-O1,O2)oxobismuth; oxo(salicylato)bismuth; basic bismuth salicylate; bismuth oxysalicylate
Trademarks: Bismed (Technilab); Jatrox (Procter & Gamble); Pepto-Bismol (Procter & Gamble)
Molecular Formula: C7H5BiO4
Molecular Weight: 362.09
Percent Composition: C 23.22%, H 1.39%, Bi 57.72%, O 17.67%
Literature References: Prepn: Fischer, Grützner, Arch. Pharm. 231, 680 (1893). Clinical trial in infant diarrhea: D. Figueroa-Quintanilla et al., N. Engl. J. Med. 328, 1653 (1993). Symposium on pharmacology and therapeutic use in gastrointestinal infections: Rev. Infect. Dis. 12, Suppl. 1, S1-S119 (1990). Mechanism of gastroprotection: D. Bagchi et al., Dig. Dis. Sci. 44, 2419 (1999).
Properties: White or nearly white amorphous or microcystalline, odorless powder. Practically insol in water.
Therap-Cat: Antidiarrheal; antiemetic.
Therap-Cat-Vet: Antidiarrheal.
Keywords: Antidiarrheal; Antiemetic. |