Title: Benzylhydrochlorothiazide
CAS Registry Number: 1824-50-6
CAS Name: 6-Chloro-3,4-dihydro-3-(phenylmethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Additional Names: 3-benzyl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 6-chloro-7-sulfamoyl-3-benzyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide; 3-benzyl-6-chloro-3,4-dihydro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide
Trademarks: Behyd (Kyorin)
Molecular Formula: C14H14ClN3O4S2
Molecular Weight: 387.86
Percent Composition: C 43.35%, H 3.64%, Cl 9.14%, N 10.83%, O 16.50%, S 16.53%
Literature References: Prepn: Werner et al., J. Am. Chem. Soc. 82, 1161 (1960); Novello et al., J. Org. Chem. 25, 970 (1960); Ugi, US 3108097 (1963).
Properties: Crystals from acetic acid + water, mp 260-262°. Also reported as crystals from water, mp 269°.
Melting point: mp 260-262°; mp 269°
Therap-Cat: Antihypertensive; diuretic.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs. |