Title: Aminopromazine
CAS Registry Number: 58-37-7
CAS Name: N,N,N¢,N¢-Tetramethyl-3-(10H-phenothiazin-10-yl)-1,2-propanediamine
Additional Names: 10-[2,3-bis(dimethylamino)propyl]phenothiazine; proquamezine; tetrameprozine
Manufacturers' Codes: RP-3828
Molecular Formula: C19H25N3S
Molecular Weight: 327.49
Percent Composition: C 69.68%, H 7.69%, N 12.83%, S 9.79%
Literature References: Prepn: Jacob et al., Compt. Rend. 243, 1637 (1956); Horclois, GB 800635 (1958 to Rhône-Poulenc).
Derivative Type: Fumarate
CAS Registry Number: 3688-62-8
Trademarks: Lispamol (Specia); Sedofarmolo (Centralvet)
Molecular Formula: (C19H25N3S)2.C4H4O4
Molecular Weight: 771.05
Percent Composition: C 65.42%, H 7.06%, N 10.90%, S 8.32%, O 8.30%
Properties: Crystals, sensitive to light, dec 166-170°. Soly at 20° (g/100 ml): water 9.0; methanol 5.0; ethanol 0.5. Very slightly sol in isopropanol, acetone. Practically insol in benzene, ether. pH of a 2% aq soln 5.0 to 7.0.
Therap-Cat: Antispasmodic.
Therap-Cat-Vet: Antispasmodic.
Keywords: Antispasmodic. |