Title: Aminitrozole
CAS Registry Number: 140-40-9
CAS Name: N-(5-Nitro-2-thiazolyl)acetamide
Additional Names: 2-acetamido-5-nitrothiazole; 2-acetylamino-5-nitrothiazole; acinitrazole; nithiamide
Trademarks: Tritheon (Ortho); Trichorad; Enheptin-A (Am. Cyanamid)
Molecular Formula: C5H5N3O3S
Molecular Weight: 187.18
Percent Composition: C 32.08%, H 2.69%, N 22.45%, O 25.64%, S 17.13%
Literature References: Prepd by nitration of 2-acetamidothiazole: Ganapathi, Venkataraman, Proc. Indian Acad. Sci. 22A, 343 (1945); Bellavita, Ann. Chim. Appl. 38, 449 (1948); Hurd, Wehrmeister, J. Am. Chem. Soc. 71, 4007 (1949); Yamamoto, J. Pharm. Soc. Jpn. 72, 1017 (1952). As an antihistomonad: Waletzky, Marson, US 2531756 (1950 to Am. Cyanamid).
Properties: Needles from alc, elongated plates from acetic acid. mp 264-265°. The commercial product may be yellow. Sol in aq solns of NaOH and NH3 with deep orange color.
Melting point: mp 264-265°
Therap-Cat: Antiprotozoal (Trichomonas).
Therap-Cat-Vet: Antihistomonad for turkeys.
Keywords: Antiprotozoal (Trichomonas). |